Necrostatin-2
货号:
11657-1mg 基本售价:
350.0 元 规格:
1 mg
产品信息
概述货号 | 11657-1mg |
描述 | Necrostatin-2 is a potent inhibitor of necroptosis with an EC50 of 50 nM in Jurkat T cells deficient of Fas-associated protein with death domain (FADD) and treated with TNF-α.1 It is approximately 4-fold more active than the (S)-enantiomer (EC50 = 230 nM). |
别名 | Cl-Necrostatin analog; |
性能供应商 | Cayman |
应用文献 |
1.Teng, X.,Degterev, A.,Jagtap, P., et al. Structure-activity relationship study of novel necroptosis inhibitors. Bioorg. Med. Chem. Lett. 15(22), 5039-5044 (2005).
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运输条件 | Wet ice in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 277.7 |
分子式 | C13H12ClN3O2 |
CAS号 | 852391-19-6 |
稳定性 | ≥ 2 years |
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