Demethoxycurcumin
货号：
10961-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 10961-1mg |
| 描述 | Demethoxycurcumin (DMC) is a natural demethoxy derivative of curcumin. More stable than curcumin in physiological media, DMC suppresses proliferation in cancer cells at 50-100 μM.1 It down-regulates the transcriptional coactivator p300, suppressing the Wnt/β-catenin pathway, and inhibits lipopolysaccharide induction of iNOS.2 |
| 别名 | DMC; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Sandur, S.K.,Pandley, M.K.,Ahn, K.S., et al. Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism. Carcinogenesis 28(8), 1765-1773 (2007).
2.Ryu, M.J.,Cho, M.,Song, J.Y., et al. Natural derivatives of curcumin attenuate the Wnt/β-catenin pathway through down-regulation of the transcriptional coactivator p300. Biochemical and Biophysical Research Communications 377(4), 1304-1308 (2008).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 338.4 |
| 分子式 | C20H18O5 |
| CAS号 | 22608-11-3 |
| 稳定性 | ≥ 2 years |
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