Capsaicin (technical grade)
货号：
10010743-500mg 基本售价：
350.0 元 规格：
500 mg
产品信息
概述| 货号 | 10010743-500mg |
| 描述 | Capsaicin is the primary active component of the heat and pain-eliciting lipid-soluble fraction of the Capsicumpepper.1 Capsaicin is present in natural hot pepper extracts along with a number of impurities, including dihydrocapsaicin and several lesser impurities. Separation by HPLC is required in order to obtain capsaicin of consistently high purity and reproducible quality.2 VR1 is a heat-activated calcium ion channel which functions as part of the normal nociceptive pain pathway. Capsaicin elicits a sensation of burning pain by activation of VR1 on small, non-myelinated polymodal C-type nociceptive nerve fibers.3 Chronic application of capsaicin leads to desensitization of these pain fibers and has been widely exploited in various non-prescription pain remedies. |
性能| 供应商 | Cayman |
| 应用文献 |
1.Gannett, P.M.,Nagel, D.L.,Reilly, P.J., et al. The capsaicinoids: Their separation, synthesis, and mutagenicity. The Journal of Organic Chemistry 53(5), 1064-1071 (1988).
2.Hoffman, P.G.,Lego, M.C. and Galetto, W.G. Separation and quantitation of red pepper major heat principles by reverse-phase high-pressure liquid chromatography. Journal of Agricultural and Food Chemistry 31(6), 1326-1330 (1983).
3.Caterina, M.J.,Schumacher, M.A.,Tominaga, M., et al. The capsaicin receptor: A heat-activated ion channel in the pain pathway. Nature 389, 816-824 (1997).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥60% |
| 计算分子量 | 305.4 |
| 分子式 | C18H27NO3 |
| CAS号 | 404-86-4 |
| 稳定性 | ≥ 2 years |
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