SOTS-1 (technical grade)
货号：
10009642-500ug 基本售价：
350.0 元 规格：
500 ug
产品信息
概述| 货号 | 10009642-500ug |
| 描述 | Superoxide radical anion is a toxic by-product of mitochondrial respiration that is formed from approximately 1-4% of the oxygen metabolized by aerobic organisms. SOTS-1 is an azo-compound that can be thermally decomposed in aqueous solution to generate superoxide radical anion at a constant, controlled rate. More specifically, SOTS-1 thermally decomposes to form an intermediate that reacts with oxygen at the diffusion-controlled limit to generate superoxide radical anion. The decay of SOTS-1 into the intermediate follows first order kinetics, and exhibits a half-life of 4900 seconds at physiological pH and temperature.1,2 This allows for study of the effect of superoxide on biologically relevant systems in a controlled environment that closely mimics conditions in vivo. |
| 别名 | Superoxide Thermal Source;Di-(4-Carboxybenzyl)Hyponitrite; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Konya, K.G.,Paul, T.,Lin, S., et al. Laser flash photolysis studies on the first superoxide thermal source. First direct measurements of the rates of solvent-assisted 1,2-hydrogen atom shifts and a proposed new mechanism for this unusual rearrangement. Journal of the American Chemical Society 122, 7518-7527 (2000).
2.Ingold, K.U.,Paul, T.,Young, M.J., et al. Invention of the first azo compound to serve as a superoxide thermal source under physiological conditions: Concept, synthesis, and chemical properties. Journal of the American Chemical Society 119, 12364-12365 (1997).
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| 运输条件 | Dry ice in continental US; may vary elsewhere |
| 存放说明 | -80 |
| 纯度 | ≥80% |
| 计算分子量 | 330.3 |
| 分子式 | C16H14N2O6 |
| CAS号 | 223507-96-8 |
| 稳定性 | ≥ 1 year |
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