| 货号 | 10008202-5000mg |
| 描述 | Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of the normal human dietary fat intake. Palmitic acid also makes up approximately 25% of the total plasma fatty acids in plasma lipoproteins.1 Saturated fatty acids induce the expression of cyclooxygenase-2 and, after protein acylation, are used to confer lipid anchoring to a variety of signaling molecules.2,3,4,5,6 Palmitic acid ethyl ester is a neutral, lipid-soluble form of the free acid. It is one of the fatty acid ethyl esters that increase cytosolic Ca2+ concentration leading to pancreatic acinar cell injury due to excessive consumption of ethanol.7 |
| 别名 | Ethyl hexadecanoate;Ethyl palmitate; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Santos, M.J.,López-Jurado, M.,Llopis, J., et al. Influence of dietary supplementation with fish oil on plasma fatty acid composition in coronary heart disease patients. Annuals of Nutrition and Metabolism 39, 52-62 (1995). 2.Dietzen, D.J.,Hastings, W.R., and Lublin, D.M. Caveolin is palmitoylated on multiple cysteine residues. Palmitoylation is not necessary for localization of caveolin to caveolae. The Journal of Biological Chemisty 270, 6838-6842 (1995). 3.Robinson, L.J., and Michel, T. Mutagenesis of palmitoylation sites in endothelial nitric oxide synthase identifies a novel motif for dual acylation and subcellular targeting. Proceedings of the National Academy of Sciences of the United States of America 92, 11776-11780 (1995). 4.Topinka, J.R., and Bredt, D.S. N-terminal palmitoylation of PSD-95 regulates association with cell membranes and interaction with K+ channel Kv1.4. Neuron 20, 125-134 (1998). 5.Lee, J.Y.,Sohn, K.H.,Rhee, S.H., et al. Saturated fatty acids, but not unsaturated fatty acids, induced the expression of cyclooxygenase-2 mediated through toll-like receptor 4. The Journal of Biological Chemisty 276(20), 16683-16689 (2001). 6.Miggin, S.M.,Lawler, O.A., and Kinsella, B.T. Palmitoylation of the human prostacyclin receptor. Functional implications of palmitoylation and isoprenylation. The Journal of Biological Chemisty 278(9), 6947-6958 (2003). 7.Chen, N.,Appell, M.,Berfield, J.L., et al. Inhibition by arachidonic acid and other fatty acids of dopamine uptake at the human dopamine transporter. European Journal of Pharmacology 478, 89-95 (2003). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | >98% |
| 计算分子量 | 284.5 |
| 分子式 | C18H36O2 |
| CAS号 | 628-97-7 |
| 稳定性 | ≥ 1 year |
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