D-erythro-Sphingosine C-20
货号：
10007903-500ug 基本售价：
350.0 元 规格：
500 ug
产品信息
概述| 货号 | 10007903-500ug |
| 描述 | Sphingosines are long-chain base precursors of cellular sphingolipids used directly in the synthesis of ceramide, which in combination with sialic acid forms ganglioside. Sphingosine can exist in four stereoisomers, however only D-erythro-sphingosine occurs naturally. Compared to other sphingolipids throughout the body, which are predominantly composed of C-18 sphingosine, only central nervous system (CNS) gangliosides contain significant amounts of D-erythro-sphingosine C-20.1,2 The concentration of D-erythro-sphingosine C-20 within mammalian brain gangliosides apparently increases with developmental maturation.1,2 Furthermore, the ratio of C-18 to C-20 sphingosine in the brain is thought to be related to some nervous system degeneration processes.1,2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Valsecchi, M.,Chigorno, V.,Nicolini, M., et al. Changes of free long-chain bases in neuronal cells during differentiation and aging in culture. Journal of Neurochemistry 67, 1866-1871 (1996).
2.Sonnino, S., and Chigorno, V. Ganglioside molecular species containing C18-and C20-sphingosine in mammalian nervous tissues and neuronal cell cultures. Biochimica et Biophysica Acta 1469, 63-77 (2000).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 327.6 |
| 分子式 | C20H41NO2 |
| CAS号 | 6918-49-6 |
| 稳定性 | ≥ 2 years |
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