Microcystin-LR
货号：
10007188-50ug 基本售价：
350.0 元 规格：
50 ug
产品信息
概述| 货号 | 10007188-50ug |
| 描述 | Microcystins are hepatotoxic cyclic heptapeptide toxins produced by cyanobacteria.1 They are responsible for periodic poisonings of humans and livestock drinking fresh water where the blue-green algae are endemic. Microcystin-LR is a selective inhibitor of protein phosphatase 2A (PP2A) (IC50= 0.04 nM) and will completely inhibit this enzyme without affecting PP1 when used at a concentration of 0.5 nM.2 The PP1 IC50 is about 1.7 nM. Microcystins are at least 10 times more potent as serine/threonine PP inhibitors than okadaic acid, another microalgal toxin also used for this purpose. |
| 别名 | Cyanoginosin-LR;Toxin T 17 (Microcystis aeruginosa); |
性能| 供应商 | Cayman |
| 应用文献 |
1.Rinehart, K.L.,Harada, K.i.,Namikoshi, M., et al. Nodularin, microcystin, and the configuration of Adda. Journal of the American Chemical Society 110, 8557-8558 (1988).
2.Honkanen, R.E.,Zwiller, J.,Moore, R.E., et al. Characterization of microcystin-LR, a potent inhibitor of Type 1 and Type 2A protein phosphatases. The Journal of Biological Chemisty 265(32), 19401-19404 (1990).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 995.2 |
| 分子式 | C49H74N10O12 |
| CAS号 | 101043-37-2 |
| 稳定性 | ≥ 1 year |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
