Prostaglandin Bx
货号：
11510-500ug 基本售价：
336.0 元 规格：
500 ug
产品信息
概述| 货号 | 11510-500ug |
| 描述 | PGBx is a mixture of oligomers of PGB1 with a molecular weight of 1,000-1,500. It has antioxidant and free radical trapping activity that was first studied in isolated mitochondria.1 PGBx has anti-inflammatory and cytoprotective activity which may be attributed to inhibition of the 14 kDa sPLA2.2,3 At a dose of 1 mg/kg, PGBx significantly reduces the incidence of ulcers in rats.2 |
| 别名 | PGBx; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Polis, B.D.,Polis, E., and Kwong, S. Protection and reactivation of oxidative phosphorylation in mitochondria by a stable free-radical prostaglandin polymer (PGBχ). Proceedings of the National Academy of Sciences of the United States of America 76, 1598-1602 (1979).
2.Kumashiro, R.,Devlin, T.M.,Kholoussy, A.M., et al. Prostaglandin Bχ in the prevention of stress ulcers in rats. International Surgery 70, 247-250 (1985).
3.Franson, R.C.,Rosenthal, M.D., and Regelson, W. Mechanism(s) of cytoprotective and anti-inflammatory activity of PGB1 oligomers: PGBx has potent anti-phospholipase A2 and anti-oxidant activity. Prostaglandins, Leukotrienes and Essential Fatty Acids 43, 63-70 (1991).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | Mixture of oligomers |
| 计算分子量 | 1 |
| 分子式 | (PGB)n n=3-5 |
| CAS号 | 39306-29-1 |
| 稳定性 | ≥ 1 year |
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