S-ethyl Isothiourea (hydrobromide)
货号：
81275-100mg 基本售价：
322.0 元 规格：
100 mg
产品信息
概述| 货号 | 81275-100mg |
| 描述 | S-ethyl Isothiourea (SEIT) is a potent inhibitor of NOS in vitro but lacks good in vivo efficacy due to poor cellular penetration. The Ki values are 19, 39, and 29 nM using purified human iNOS, eNOS, and nNOS, respectively.1,2,3 |
| 别名 | Ethiron bromide;2-Ethyl-2-thiopseudourea hydrobromide;SEIT (HBr);WR 539; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Garvey, E.P.,Oplinger, J.A.,Tanoury, G.J., et al. Potent and selective inhibition of human nitric oxide synthases. Inhibition by non-amino acid isothioureas. The Journal of Biological Chemisty 269, 26669-26676 (1994).
2.Nakane, M.,Klinghofer, V.,Kuk, J.E., et al. Novel potent and selective inhibitors of inducible nitric oxide synthase. Molecular Pharmacology 47, 831-834 (1995).
3.Southan, G.J.,Szabó, C. and Thiemermann, C. Isothioureas: Potent inhibitors of nitric oxide synthases with variable isoform selectivity. British Journal of Pharmacology 114, 510-516 (1995).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 185.1 |
| 分子式 | C3H8N2S ?HBr |
| CAS号 | 1071-37-0 |
| 稳定性 | ≥ 1 year |
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