Ursolic Acid
货号：
10072-50mg 基本售价：
322.0 元 规格：
50 mg
产品信息
概述| 货号 | 10072-50mg |
| 描述 | Ursolic acid, a natural pentacyclic triterpenoid carboxylic acid, is a major component of some traditional medicine herbs, foods, and other plants that is known to possess a wide range of biological functions, such as antioxidative, antimicrobial, anti-inflammatory, and anticancer activities. Ursolic acid inhibits Na+/K+-ATPase activity (IC50 = 24.7 μM) and blocks NF-κB activation in various human cancer cells lines (10-100 μM), inhibiting cell proliferation and inducing apoptosis.1,2,3 |
| 别名 | Bungeolic Acid;Maerotaine;Malol;NSC 4060;NSC 167406;Prunol; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Yokomichi, T.,Morimoto, K.,Oshima, N., et al. Ursolic acid inhibits Na+/K+-ATPase activity and prevents TNF-α-induced gene expression by blocking amino acid transport and cellular protein synthesis. Biomolecules 1, 32-47 (2011).
2.Shishodia, S.,Majumdar, S.,Banerjee, S., et al. Ursolic acid inhibits nuclear factor-κB activation induced by carcinogenic agents through suppression of I κBα kinase and p65 phosphorylation: Correlation with down-regulation of cyclooxygenase 2, matrix metalloproteinase 9, and cyclin D1. Cancer Research 63, 4375-4383 (2003).
3.Wang, X.,Zhang, F.,Yang, L., et al. Ursolic acid inhibits proliferation and induces apoptosis of cancer cells in vitro and in vivo. Journal of Biomedicine and Biotechnology 1-8 (2011).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 456.7 |
| 分子式 | C30H48O3 |
| CAS号 | 77-52-1 |
| 稳定性 | ≥ 2 years |
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