| 货号 | 360906-100ug |
| 描述 | Lyso-PAF C-16-d4 contains four deuterium atoms at the 7, 7, 8, and 8 positions of the hexadecyl moiety. It is intended for use as an internal standard for the quantification of PAF C-16 by GC- or LC-mass spectrometry. Lyso-PAF C-16 can be formed by either the action of PAF-AH on PAF C-16,1 or by the action of a CoA-independent transacylase on 1-O-hexadecyl-2-acyl-glycerophosphocholine.2,3 Lyso-PAF C-16 is a substrate for either PAF C-16 formation by the remodeling pathway4 or selective acylation with arachidonic acid by a CoA-independent transacylase.5 |
| 别名 | Lyso-Platelet-activating Factor C-16-d4; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Stafforini, D.M.,Prescott, S.M., and McIntyre, T.M. Human plasma platelet-activating factor acetylhydrolase. The Journal of Biological Chemisty 262, 4223-4230 (1987). 2.Uemura, Y.,Lee, T., and Snyder, F. A coenzyme A-independent transacylase is linked to the formation of platelet-activating factor (PAF) by generating the lyso-PAF intermediate in the remodeling pathway. The Journal of Biological Chemisty 266, 8268-8272 (1991). 3.Venable, M.E.,Nieto, M.L.,Schmitt, J.D., et al. Conversion of 1-O-[3H]alkyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine to lyso platelet-activating factor by the CoA-independent transacylase in membrane fractions of human neutrophils. The Journal of Biological Chemisty 266, 18691-18698 (1991). 4.Prescott, S.M.,Zimmerman, G.A., and McIntyre, T.M. Platelet-activating factor. The Journal of Biological Chemisty 265, 17381-17384 (1990). 5.Venable, M.E.,Olson, S.C.,Nieto, M.L., et al. Enzymatic studies of lyso platelet-activation factor acylation in human neutrophils and changes upon stimulation. The Journal of Biological Chemisty 268, 7965-7975 (1993). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥99% deuterated forms (d1-d4) |
| 计算分子量 | 485.7 |
| 分子式 | C24H48D4NO6P |
| CAS号 | 201216-37-7 |
| 稳定性 | ≥ 1 year |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |