H-Gly-Pro-Arg-Pro-OH (acetate)
货号：
21163-1mg 基本售价：
294.0 元 规格：
1 mg
产品信息
概述| 货号 | 21163-1mg |
| 描述 | H-Gly-Pro-Arg-Pro-OH (GPRP) is a peptide corresponding partly to the amino terminus of the Aα chain and Bβ chain of fibrin. It inhibits the spontaneous polymerization of fibrin monomers and also inhibits ADP-induced platelet aggregation (IC50 = 3 mM).1,2,3 GPRP binds to the fibrinogen D domain, inhibiting the ability of fibrinogen to bind to the platelet membrane glycoprotein GPIIb/IIIa.1,2 |
| 别名 | GPRP; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Laudano, A.P. and Doolittle, R.F. Synthetic peptide derivatives that bind to fibrinogen and prevent the polymerization of fibrin monomers. Proc. Natl. Acad. Sci. USA 75(7), 3085-3089 (1978).
2.Plow, E.F. and Marguerie, G. Inhibition of fibrinogen binding to human platelets by the tetrapeptide glycyl-L-prolyl-L-arginyl-L-proline. Proc. Natl. Acad. Sci. USA 79(12), 3711-3715 (1982).
3.Adelman, B.,Gennings, C.,Stony, J., et al. Synergistic inhibition of platelet aggregation by fibrinogen-related peptides. Circ. Res. 67(4), 941-947 (1990).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 485.5 |
| 分子式 | C18H31N7O5 • C2H4O2 |
| CAS号 | 157009-81-9 |
| 稳定性 | ≥ 2 years |
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