| 货号 | 10012600-10mg |
| 描述 | Myricetin is a flavonoid compound found in many fruits and vegetables, including red wine, that acts as a powerful antioxidant.1 Myricetin inhibits TBARS formation with an IC50 value of 6.34 and at 20 µM, blocks oxLDL uptake by U937-derived macrophages, reducing CD36 expression.2 Myricetin demonstrates potent chemopreventative potential by binding JAK1/STAT3 to inhibit the neoplastic transformation of murine JB6 P+ cells and inhibiting MEK1 kinase activity.3,4 |
| 别名 | Cannabiscetin;NSC 407290; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Bennett, C.J.,Caldwell, S.T.,McPhail, D.B., et al. Potential therapeutic antioxidants that combine the radical scavenging ability of myricetin and the lipophilic chain of vitamin E to effectively inhibit microsomal lipid peroxidation. Bioorganic & Medicinal Chemistry 12, 2079-2098 (2004). 2.Lian, T.-W.,Wang, L.,Lo, Y.-H., et al. Fisetin, morin and myricetin attenuate CD36 expression and oxLDL uptake in U937-derived macrophages. Biochimica et Biophysica Acta 1781, 601-609 (2008). 3.Kumamoto, T.,Fujii, M. and Hou, D.X. Myricetin directly targets JAK1 to inhibit cell transformation. Cancer Letters 275, 17-26 (2009). 4.Lee, K.W.,Kang, N.J.,Rogozin, E.A., et al. Myricetin is a novel natural inhibitor of neoplastic cell transformation and MEK1. Carcinogenesis 28(9), 1918-1927 (2007). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 318.2 |
| 分子式 | C15H10O8 |
| CAS号 | 529-44-2 |
| 稳定性 | ≥ 1 year |
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