(±)-SDZ-201 106
货号：
21356-10mg 基本售价：
280.0 元 规格：
10 mg
产品信息
概述| 货号 | 21356-10mg |
| 描述 | (±)-SDZ-201106 is a diphenylpiperazinylindole derivative that prolongs the open state of cardiac voltage-gated Na+ channels. It has been shown to increase net Na+ influx and the activity of reverse mode Na+/Ca2+ exchange, which leads to an increase in intracellular Ca2+, as well as to partially inhibit the Na+ pump in cardiac myocytes.1 (±)-SDZ-201106 is also reported to act as an open-channel blocker of delayed-rectifier K+ channels in NG108-15 neuronal cells.2 |
| 别名 | DPI 201-106; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Kaumann, A.H.,Richards, D.E., and Russell, D.A. Inhibition of the sodium pump by cardioactive DPI 201-106. Br. J. Pharmacol. 91(1), 3-5 (1987).
2.Wang, Y.-J.,Lin, M.-W.,Lin, A.-A., et al. Evidence for state-dependent block of DPI 201-106, a synthetic inhibitor of Na+ channel inactivation, on delayed-rectifier K+ current in pituitary tumor (GH3) cells. J. Physiol. Pharmacol. 59(3), 409-423 (2008).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 466.6 |
| 分子式 | C29H30N4O2 |
| CAS号 | 97730-95-5 |
| 稳定性 | ≥ 2 years |
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