| 货号 | 21212-1g |
| 描述 | Bacitracin is a cyclic polypeptide antibiotic that was first isolated from B. licheniformis.1 Formulations containing bacitracin, often combined with other antibiotics, are used for topical treatment of infections in humans and animals.2,3 The activity of bacitracin can be enhanced by zinc.4 Bacitracin sequesters C55-isopropyl pyrophosphate (IPP), a lipid carrier in peptidoglycan synthesis, and in this way disrupts cell wall biosynthesis.2,3 |
| 别名 | Bacifarmin;Bacifarmin (zinc); |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Katz, E. and Demain, A.L. The peptide antibiotics of Bacillus: Chemistry, biogenesis, and possible functions. Bacteriol. Rev. 41(2), 449-474 (1977). 2.Butaye, P.,Devriese, L.A. and Haesebrouck, F. Antimicrobial growth promoters used in animal feed: Effects of less well known antibiotics on gram-positive bacteria. Clin. Microbiol. Rev. 16(2), 175-188 (2003). 3.Chancey, S.T.,Zähner, H. and Stephens, D.S. Acquired inducible antimicrobial resistance in Gram-positive bacteria. Future Microbiol. 7(8), 959-978 (2012). 4.Astiazarán-García, H.,Iñigo-Figueroa, G.,Quihui-Cota, L., et al. Crosstalk between zinc status and Giardia infection: A new approach. Nutrients 7(6), 4438-4452 (2015). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥70% (Bacitracin A,B1,B3 mixture) |
| 计算分子量 | 1486.1 |
| 分子式 | C66H101N17O16S • Zn |
| CAS号 | 1405-89-6 |
| 稳定性 | ≥ 2 years |
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