Aripiprazole
货号：
19989-5mg 基本售价：
280.0 元 规格：
5 mg
产品信息
概述| 货号 | 19989-5mg |
| 描述 | Aripiprazole is a quinolinone derivative and atypical antipsychotic drug.1 It is metabolized by cytochrome P450 isoforms 3A4 and 2D6 to an active metabolite, dehydroaripiprazole, and both compounds act as a dopamine system stabilizers.2,3 |
| 别名 | OPC 31;OPC 14597; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Swainston Harrison, T., and Perry, C.M. Aripiprazole: A review of its use in schizophrenia and schizoaffective disorder. Drugs 64(15), 1715-1736 (2004).
2.Pettersson, F.,Pontén, H.,Waters, N., et al. Synthesis and evaluation of a set of 4-phenylpiperidines and 4-phenylpiperazines as D2 receptor ligands and the discovery of the dopaminergic stabilizer 4-[3-(methylsulfonyl)phenyl]-1-propylpiperidine (huntexil, pridopidine, ACR16). Journal of Medicinal Chemistry 53, 2510-2520 (2013).
3.Kim, J.R.,Seo, H.B.,Cho, J.Y., et al. Population pharmacokinetic modelling of aripiprazole and its active metabolite, dehydroaripiprazole, in psychiatric patients. British Journal of Clinical Pharmacology 66(6), 802-810 (2008).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 448.4 |
| 分子式 | C23H27Cl2N3O2 |
| CAS号 | 129722-12-9 |
| 稳定性 | ≥ 2 years |
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