货号 | 19257-10mg |
描述 | Biliverdin is a green bile pigment produced from the oxidation of heme in a reaction catalyzed by heme oxygenase and is further reduced to bilirubin (Item No. 17161) by biliverdin reductase.1,2 Biliverdin regulates the cellular heme degradation process by inhibiting substrates from binding to the catalytic site of heme oxygenase. Bile pigments such as biliverdin are known to possess anti-mutagenic and antioxidant properties.3,4 |
供应商 | Cayman |
应用文献 | |
1.Liu, Y.,Moënne-Loccoz, P.,Loehr, T.M., et al. Heme oxygenase-1, intermediates in verdoheme formation and the requirement for reduction equivalents. The Journal of Biological Chemisty 272, 6909-6917 (1997). 2.Maines, M.D. The heme oxygenase system: A regulator of second messenger gases. Annual Reviews of Pharmacology and Toxicology 37, 517-554 (1997). 3.Bulmer, A.C.,Ried, K.,Blanchfield, J.T., et al. The anti-mutagenic properties of bile pigments. Mutation Research 658(1-2), 28-41 (2008). 4.Mölzer, C.,Huber, H.,Steyrer, A., et al. In vitro antioxidant capacity and antigenotoxic properties of protoporphyrin and structurally related tetrapyrroles. Free Rad.Res. 46(11), 1369-1377 (2012). | |
运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% mixture of isomers |
计算分子量 | 619.1 |
分子式 | C33H34N4O6 • HCl |
CAS号 | 856699-18-8 |
稳定性 | ≥ 2 years |
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