| 货号 | 16063-100mg |
| 描述 | Corticosterone is a steroid hormone produced in the cortex of the adrenal glands that binds to both glucocorticoid and mineralocorticoid receptors.1 It is produced in response to ACTH (corticotropic hormone) and is the precursor to aldosterone synthesis.2 Since the production of glucocorticoids is increased by stress, it is often used as a biomarker of stress.3 Plasma corticosterone levels have a circadian variation and corticosterone may be important in the regulation of the sleep-wake cycle.4,5 |
| 别名 | 17-deoxy Cortisol;11β,21-DHP;NSC 9705;11β,21-dihydroxy Progesterone; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Lu, N.Z.,Wardell, S.E.,Burnstein, K.L., et al. International Union of Pharmacology. LXV. The pharmacology and classification of the nuclear receptor superfamily: Glucocorticoid, mineralocorticoid, progesterone, and androgen receptors. Pharmacological Reviews 58(4), 782-797 (2006). 2.Palme, R.,Rettenbacher, C.,Touma, C., et al. Stress hormones in mammals and birds: comparative aspects regarding metabolism, excretion, and noninvasive measurement in fecal samples. Annals of the New York Academy of Sciences 1040, 162-171 (2005). 3.Goymann, W.,Möstl, E. and Gwinner, E. Corticosterone metabolites can be measured noninvasively in excreta of European stonechats (Saxicola torquata rubicola). The Auk 119(4), 1167-1173 (2002). 4.Vázquez-Palacios, G.,Retana-Márquez, S.,Bonilla-Jaime, H., et al. Further definition of the effect of corticosterone on the sleep-wake pattern in the male rat. Pharmacology, Biochemistry, and Behavior 70, 305-310 (2001). 5.Millspaugh, J.J.,Washburn, B.E.,Milanick, M.A., et al. Effects of heat and chemical treatments on fecal glucocorticoid measurements: Implications for sample transport. Wildlife Society Bulletin 31(2), 399-406 (2003). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 346.5 |
| 分子式 | C21H30O4 |
| CAS号 | 50-22-6 |
| 稳定性 | ≥ 2 years |
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