AM404
货号：
90060-5mg 基本售价：
266.0 元 规格：
5 mg
产品信息
概述| 货号 | 90060-5mg |
| 描述 | AM404 is an analog of arachidonyl ethanolamide (AEA) which potentiates the activity of endogenous AEA by blocking its re-uptake into presynaptic neurons. AM404 selectively inhibits the carrier-mediated transport of AEA without affecting anandamide hydrolysis. It inhibits the transport of AEA with an IC50 of 1 µM in rat neurons and 5 µM in rat astrocytes. In in vivo models, AM404 enhances and prolongs exogenous AEA-induced analgesia at a dose of 10 mg/kg.1 |
| 别名 | 4-HPA;N-(4-hydroxyphenyl)-Arachidonoyl Amide; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Beltramo, M.,Stella, N.,Calignano, A., et al. Functional role of high-affinity anandamide transport, as revealed by selective inhibition. Science 277, 1094-1097 (1997).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 395.6 |
| 分子式 | C26H37NO2 |
| CAS号 | 183718-77-6 |
| 稳定性 | ≥ 1 year |
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