| 货号 | 80230-5mg |
| 描述 | NG,NG-dimethyl-L-Arginine (ADMA) is an endogenous nitric oxide synthase inhibitor. ADMA concentrations increase in several disease states including renal failure, muscular dystrophy, hypercholesterolemia, and pregnancy with preeclampsia, but its precise role in these diseases has not been elucidated.1,2,3,4 |
| 别名 | ADMA; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Vallance, P.,Leone, A.,Calver, A., et al. Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure. Lancet 339, 572-575 (1992). 2.Matsuoka, H.,Itoh, S.,Kimoto, M., et al. Asymmetrical dimethylarginine, an endogenous nitric oxide synthase inhibitor, in experimental hypertension. Hypertension 29, 242-247 (1997). 3.Jin, J.S. and DAlecy, L.G. Central and peripheral effects of asymmetric dimethylarginine, an endogenous nitric oxide synthetase inhibitor. Journal of Cardiovascular Pharmacology 28, 439-446 (1996). 4.Holden, D.P.,Fickling, S.A.,Whitley, G.S.J., et al. Plasma concentrations of asymmetric dimethylarginine, a natural inhibitor of nitric oxide synthase, in normal pregnancy and preeclampsia. American Journal of Obstetics and Gynecology 178, 551-556 (1998). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 275.2 |
| 分子式 | C8H18N4O2 • 2HCl |
| CAS号 | 220805-22-1 |
| 稳定性 | ≥ 1 year |
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