| 货号 | 19871-5g |
| 描述 | Ferulic acid is a hydroxycinnamic acid with antioxidant properties that is present in the cell walls of plants such as wheat, rice, peanuts, coffee, oranges, and apples. Its antioxidant activity has been shown to act synergistically with vitamins C and E, reducing thymine dimer formation in skin exposed to UVB irradiation.1,2 Animal and in vitro studies suggest that ferulic acid and its derivatives may have direct antitumor activity and pro-apoptotic effects in cancer cells.3,4 Ferulic acid has also been examined in the process of skin lightening due to its ability to inhibit tyrosinase, the key enzyme in melanogenesis.5 |
| 别名 | Coniferic Acid;4-hydroxy-3-Methoxycinnamic Acid;NSC 2821;NSC 51986;NSC 674320; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Lin, F.-H.,Lin, J.-Y.,Gupta, R.D., et al. Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. J. Invest. Dermatol. 125(4), 826-832 (2005). 2.Di Domenico, F.,Perluigi, M.,Foppoli, C., et al. Protective effect of ferulic acid ethyl ester against oxidative stress mediated by UVB irradiation in human epidermal melanocytes. Free Radical Research 43(4), 365-375 (2009). 3.Hosoda, A.,Ozaki, Y.,Kashiwada, A., et al. Syntheses of ferulic acid derivatives and their suppressive effects on cyclooxygenase-2 promoter activity. Bioorganic & Medicinal Chemistry 10, 1189-1196 (2002). 4.Huang, M.T.,Smart, R.C.,Wong, C., et al. Inhibitory effect of curcumin, chlorogenic acid, caffeic acid, and ferulic acid on tumor promotion in mouse skin by 12-O-tetradecanoylphorbol-13-acetate. Cancer Research 48, 5941-5946 (1988). 5.Smit, N.,Vicanova, J. and Pavel, S. The hunt for natural skin whitening agents. International Journal of Molecular Sciences 10(12), 5326-5349 (2009). | |
| 运输条件 | Ambient in continental US; may vary elsewhere |
| 存放说明 | 22 |
| 纯度 | ≥98% |
| 计算分子量 | 194.2 |
| 分子式 | C10H10O4 |
| CAS号 | 1135-24-6 |
| 稳定性 | ≥ 2 years |
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