Atropine
货号：
12008-500mg 基本售价：
266.0 元 规格：
500 mg
产品信息
概述| 货号 | 12008-500mg |
| 描述 | Atropine is a naturally occurring tropane alkaloid extracted from plants of the family Solanaceae including deadly nightshade (A. belladonna). It is a non-selective, competitive antagonist of the muscarinic acetylcholine receptor types M1, M2, M3, M4, and M5 (pKBs range from 8.9-9.8).1 Atropine increases firing of the sinoatrial node and conduction through the atrioventricular node of the heart, opposes the actions of the vagus nerve, blocks acetylcholine receptor sites, and decreases bronchial secretions.2 It is classified as an anticholinergic (parasympatholytic) drug and commonly used to dilate the pupils, increase heart rate, reduce salivation and other secretions, and as an antidote against organophosphate poisoning.3 |
| 别名 | DL-Hyoscyamine;Tropine tropate; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Caulfield, M.P., and Birdsall, N.J.M. International union of pharmacology. XVII. Classification of muscarinic acetylcholine receptors. Pharmacological Reviews 50(2), 279-290 (1998).
2.Broadley, K.J., and Kelly, D.R. Muscarinic receptor agonists and antagonists. Molecules 6, 142-193 (2001).
3.Grynkiewicz, G., and Gadzikowska, M. Tropane alkaloids as medicinally useful natural products and their synthetic derivatives as new drugs. Pharmacological Reports 60, 439-463 (2008).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 289.4 |
| 分子式 | C17H23NO3 |
| CAS号 | 51-55-8 |
| 稳定性 | ≥ 2 years |
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