N-acetyl-D-Glucosamine
货号：
13136-1g 基本售价：
238.0 元 规格：
1 g
产品信息
概述| 货号 | 13136-1g |
| 描述 | N-acetyl-D-Glucosamine (GlcNAc) is a monosaccharide derivative of glucose. It is released by the action of O-GlcNAcase, in mammalian systems from proteins that have been post-translationally modified with O-GlcNAc. Levels of O-GlcNAcylation proteins from Alzheimer’s disease brain extracts are decreased as compared to that in controls, suggesting that release of GlcNAc may contribute to pathogenesis.1InE. coli, GlcNAc induces the expression of multidrug exporter genes, indicating that this sugar can alter gene expression.1 GlcNAc is also the monomeric unit of chitin, which is found in fungi and many invertebrates, including crustaceans, insects, and nematodes. For this reason, chemicals that inhibit the incorporation of GlcNAc into chitin are cytotoxic to these organisms. |
| 别名 | GlcNAc;Marine Sweet;NAG;NSC 524344; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Liu, F.,Iqbal, K.,Grundke-Iqbal, I., et al. O-GlnNAcylation regulates phosphorylation of tau: A mechanism involved in Alzheimer’s disease. Proceedings of the National Academy of Sciences of the United States of America 101(29), 10804-10809 (2004).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 221.2 |
| 分子式 | C8H15NO6 |
| CAS号 | 7512-17-6 |
| 稳定性 | ≥ 2 years |
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