GW 610
货号：
10008313-1mg 基本售价：
238.0 元 规格：
1 mg
产品信息
概述| 货号 | 10008313-1mg |
| 描述 | GW 610 is an antitumor benzothiazole that shows growth-inhibitory activity against several cancer cell lines. In MCF-7 and MDA 468 human cancer cell lines, potent antiproliferative activity (growth inhibition (GI50)< 0.1 nM) was observed.1 Potent and selective activity was also observed in the NCI 60 human cancer cell line panel. In contrast with previously reported 2-(4-aminophenyl)benzothiazoles, GW 610 is not reliant on induction of cytochrome P 1A1 (CYP1A1) expression for antitumor activity. |
| 别名 | NSC 721648; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Mortimer, C.G.,Wells, G.,Crochard, J.P., et al. Antitumor benzothiazoles. 26. 2-(3,4-Dimethoxyphenyl)-5-fluorobenzothiazole (GW 610, NSC 721648), a simple fluorinated 2-arylbenzothiazole, shows potent and selective inhibitory activity against lung, colon, and breast cancer cell lines. Journal of Medicinal Chemistry 49, 179-185 (2006).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 289.3 |
| 分子式 | C15H12FNO2S |
| CAS号 | 872726-44-8 |
| 稳定性 | ≥ 2 years |
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