Oleic Acid
货号：
90260-1000mg 基本售价：
224.0 元 规格：
1 g
产品信息
概述| 货号 | 90260-1000mg |
| 描述 | Oleic acid is a monounsaturated fatty acid and is one of the major components of membrane phospholipids. Oleic acid contributes about 17% of the total fatty acids esterified to phosphatidylcholine, the major phospholipid class in porcine platelets.1 Oleic acid inhibits collagen-stimulated platelet aggregation by approximately 90% when used at a concentration of 10 µg/ml.1 fMLF-induced neutrophil aggregation and degranulation is inhibited by 55% and 68%, respectively, using 5 µM oleic acid. This inhibition is comparable to that observed using arachidonic acid under the same conditions.2 Oleic acid, whether applied extracellularly (EC50 = ~60 µM) to human platelets or released from membrane phospholipids, causes an increase in intracellular calcium levels.3 |
| 别名 | cis-9-Octadecenoic acid; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Wahle, K.W.J., and Peacock, L.I.L. Effects of isomeric cis and trans eighteen carbon monounsaturated fatty acids on porcine platelet function. Biochimica et Biophysica Acta 1301, 141-149 (1996).
2.Naccache, P.H.,Moiski, T.F.P.,Volpi, M., et al. Modulation of rabbit neutrophil aggregation and degranulation by free fatty acids. Journal of Leukocyte Biology 36, 333-340 (1984).
3.Siafaka-Kapadai, A.,Hanahan, D.J., and Javors, M.A. Oleic acid-induced Ca2+ mobilization in human platelets: Is oleic acid an intracellular messenger? Journal of Lipid Mediators and Cell Signalling 15, 215-232 (1997).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 282.5 |
| 分子式 | C18H34O2 |
| CAS号 | 112-80-1 |
| 稳定性 | ≥ 2 years |
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