| 货号 | 9000324-1mg |
| 描述 | Spironolactone is structurally categorized as a synthetic steroid hormone antagonist. It is a multi-target drug with diverse clinical applications.1,2,3,4 Diuretics, including spironolactone, have been abused as performance-enhancing drugs and masking agents in sports doping.5 |
| 别名 | NSC 150399;SC-9420; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Chun, T.Y.,Bloem, L.J., and Pratt, J.H. Aldosterone inhibits inducible nitric oxide synthase in neonatal rat cardiomyocytes. Endocrinology 144(5), 1712-1717 (2003). 2.Gerber, J.G.,Freed, C.R., and Nies, A.S. Antihypertensive pharmacology. West.J.Med. 132(5), 430-439 (1980). 3.Lehmann, J.M.,McKee, D.D.,Watson, M.A., et al. The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions. Journal of Clinical Investigation 102(5), 1016-1123 (1998). 4.Larik, F.A.,Saaed, A.,Shahzad, D., et al. Synthetic approaches towards the multi target drug spironolactone and its potent analogues/derivatives. Steroids 118, 76-92 (2017). 5.Cadwallader, A.B.,de la Torre, X.,Tieri, A., et al. The abuse of diuretics as performance-enhancing drugs and masking agents in sport doping: Pharmacology, toxicology and analysis. Br. J. Pharmacol. 161(1), 1-16 (2010). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 416.6 |
| 分子式 | C24H32O4S |
| CAS号 | 52-01-7 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |