Triamterene
货号：
21242-1g 基本售价：
210.0 元 规格：
1 g
产品信息
概述| 货号 | 21242-1g |
| 描述 | Triamterene is an inhibitor of the epithelial sodium channel ENaC that increases renal sodium excretion and decreases potassium excretion. It inhibits rat ENaC with an IC50 value of 4.5 µM.1 Diuretics, including triamterene, have been abused as performance-enhancing drugs and masking agents in sports doping.2 |
| 别名 | NSC 77625;SKF 8542;2,4,7-Triamino-6-phenylpteridine; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Kellenberger, S.,Gautschi, I. and Schlid, L. Mutations in the epithelial Na+ channel ENaC outer pore disrupt amiloride block by increasing its dissociation rate. Mol. Pharmacol. 64(4), 848-856 (2003).
2.Cadwallader, A.B.,de la Torre, X.,Tieri, A., et al. The abuse of diuretics as performance-enhancing drugs and masking agents in sport doping: Pharmacology, toxicology and analysis. Br. J. Pharmacol. 161(1), 1-16 (2010).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 253.3 |
| 分子式 | C12H11N7 |
| CAS号 | 396-01-0 |
| 稳定性 | ≥ 2 years |
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