| 货号 | 20976-25g |
| 描述 | Sulfamethazine is an antibacterial sulfonamide. Like other sulfonamides, sulfamethazine is bacteriostatic, competitively inhibiting dihydropteroate synthase to block folate synthesis and inhibit growth and multiplication.1 Sulfamethazine is metabolized by cytochrome P450 isoforms and arylamine N-acetyltransferase 2 in a sex-dependent manner.2,3,4 |
| 别名 | NSC 67457;NSC 683529;Sulfadimethyldiazine;Sulfadimidine; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Allegra, C.J.,Boarman, D.,Kovacs, J.A., et al. Interaction of sulfonamide and sulfone compounds with Toxoplasma gondii dihydropteroate synthase. J. Clin. Invest. 85(2), 371-379 (1990). 2.Badawi, A.F.,Hirvonen, A.,Bell, D.A., et al. Role of aromatic amine acetyltransferases, NAT1 and NAT2, in carcinogen-DNA adduct formation in the human urinary bladder. Cancer Res. 55(22), 5230-5237 (1995). 3.Meyer, U.A. Interaction of sulfonamide and sulfone compounds with Toxoplasma gondii dihydropteroate synthase. Environ. Health Perspect. 102(Suppl 6), 213-216 (1994). 4.Witkamp, R.F.,Nijmeijer, S.M.,Yun, H., et al. Sulfamethazine as a model compound to assess sex hormone-dependent cytochrome P-450 activity in rats. Drug Metab. Dispos. 32(3), 441-446 (1993). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | 22 |
| 纯度 | ≥98% |
| 计算分子量 | 278.3 |
| 分子式 | C12H14N4O2S |
| CAS号 | 57-68-1 |
| 稳定性 | ≥ 2 years |
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