| 货号 | 20828-10g |
| 描述 | 2,3-Butanedione-2-monoxime (BDM) is a non-selective, reversible myosin ATPase inhibitor with phosphatase-like properties.1,2 It demonstrates direct and indirect actions on cardiac and vascular smooth muscle, inhibiting L-type Ca2+channels.3,4 BDM has been shown to be involved in a number of biological activities, including muscle contraction and synaptic transmission.1 |
| 别名 | BDM;Diacetyl Monoxime;NSC 660;NSC 116103; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Sellin, L.C. and McArdle, J.J. Multiple effects of 2,3-butanedione monoxime. Pharmacol. Toxicol. 74(6), 305-313 (1994). 2.Ostap, E.M. 2,3-Butanedione monoxime (BDM) as a myosin inhibitor. J. Muscle Res. Cell Motil. 23(4), 305-308 (2002). 3.Eisfeld, J.,Mikala, G.,Varadi, G., et al. Inhibition of cloned human L-type cardiac calcium channels by 2,3-butanedione monoxime does not require PKA-dependent phosphorylation sites. Biochem. Biophys. Res. Commun. 230(3), 489-492 (1997). 4.Adhikari, B.B. and Wang, K. Interplay of troponin- and myosin-based pathways of calcium activation in skeletal and cardiac muscle: The use of W7 as an inhibitor of thin filament activation. Biophysical Journal 86(1), 359-370 (2004). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 101.1 |
| 分子式 | C4H7NO2 |
| CAS号 | 57-71-6 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |