Isoniazid
货号：
20378-50g 基本售价：
210.0 元 规格：
50 g
产品信息
概述| 货号 | 20378-50g |
| 描述 | Isoniazid is an antibiotic that acts as a prodrug, being converted by bacterial catalase-peroxidases to form isonicotinic acyl-NADH complex, which inhibits mycolic acid biosynthesis.1 It is effective against several species of Mycobacterium, including M. tuberculosis.2,3 |
| 别名 | Isonicotinylhydrazide;NSC 9659; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Wang, F.,Langley, R.,Gulten, R., et al. Mechanism of thioamide drug action against tuberculosis and leprosy. Journal of Experimental Medicine 204(1), 72-78 (2007).
2.Phetsuksiri, B.,Baulard, A.R.,Cooper, A.M., et al. Antimycobacterial activities of isoxyl and new derivatives through the inhibition of mycolic acid synthesis. Antimicrobial Agents and Chemotherapy 43(5), 1042-1051 (1999).
3.Chang, K.C.,Yew, W.W.,Tam, C.M., et al. WHO group 5 drugs and difficult multidrug-resistant tuberculosis: A systematic review with cohort analysis and meta-analysis. Antimicrobial Agents and Chemotherapy 57(9), 4097-4104 (2013).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | 22 |
| 纯度 | ≥98% |
| 计算分子量 | 137.1 |
| 分子式 | C6H7N3O |
| CAS号 | 54-85-3 |
| 稳定性 | ≥ 2 years |
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