SKF 96365 (hydrochloride)
货号：
10009312-1mg 基本售价：
210.0 元 规格：
1 mg
产品信息
概述| 货号 | 10009312-1mg |
| 描述 | SKF 96365 inhibits the receptor-mediated influx of calcium via voltage-gated calcium channels with an IC50 value of approximately 10 µM.1 It inhibits the acetylcholine-induced depolarization of circular smooth muscle in a dose-dependent manner at 3-50 µM.2 SKF 96365 can distinguish receptor-mediated release in platelets and neutrophils from the calcium release from internal stores. However, it does not distinguish between receptor-mediated and voltage-gated release. |
性能| 供应商 | Cayman |
| 应用文献 |
1.Merritt, J.E.,Armstrong, W.P.,Benham, C.D., et al. SK&F 96365, a novel inhibitor of receptor-mediated calcium entry. Biochemistry Journal 271, 515-522 (1990).
2.Hotta, A.,Kim, Y.C.,Kakamura, E., et al. Effects of inhibitors of nonselective cation channels on the acetylcholine-induced depolarization of circular smooth muscle from the guinea-pig stomach antrum. Journal of Smooth Muscle Research 41(6), 313-327 (2005).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 402.9 |
| 分子式 | C22H26N2O3 • HCl |
| CAS号 | 130495-35-1 |
| 稳定性 | ≥ 2 years |
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