Valinomycin
货号：
10009152-5mg 基本售价：
210.0 元 规格：
5 mg
产品信息
概述| 货号 | 10009152-5mg |
| 描述 | Valinomycin is a cyclododecadepsipeptide potassium-selective ionophore antibiotic that is isolated from various strains of Streptomyces. The hydrophilic interior is the right size to accommodate the potassium ion, but not other ions, while the hydrophobic exterior allows the complex to pass through the lipid bilayer. Valinomycin induces apoptosis in several cell types, including CHO cells, by stimulating potassium efflux. Apoptotic events produced by valinomycin include phosphatidylserine membrane translocation, caspase-3 activation, and mitochondrial membrane depolarization. 1 Due to the ion-selective nature of valinomycin, it is used in ion-selective electrodes. |
| 别名 | NSC 122023; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Abdalah, R.,Wei, L.,Francis, K., et al. Valinomycin-induced apoptosis in Chinese hamster ovary cells. Neuroscience Letters 405, 68-73 (2006).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 1111.3 |
| 分子式 | C54H90N6O18 |
| CAS号 | 2001-95-8 |
| 稳定性 | ≥ 2 years |
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