O-Acetyl Salicylhydroxamic Acid
货号：
70263-1mg 基本售价：
196.0 元 规格：
1 mg
产品信息
概述| 货号 | 70263-1mg |
| 描述 | O-Acetyl Salicylhydroxamic Acid (O-ASHA) is an irreversible, non-selective inhibitor of COX-1 and COX-2. Aspirin is the best-studied example of an irreversible COX inhibitor, acting via the acetylation of the active site serine residue 529 in human COX-1. O-ASHA inhibits ovine COX-1 in a time-dependent, irreversible manner with a 50% B/B0 value of approximately 4.5 mM.1 |
| 别名 | AcSHA;O-ASHA; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Loll, P.J.,Sharkey, C.T.,OConnor, S.J., et al. O-acetylsalicylhydroxamic acid, a novel acetylating inhibitor of prostaglandin H2 synthase: structural and functional characterization of enzyme-inhibitor interactions. Molecular Pharmacology 60(6), 1407-1413 (2001).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 195.2 |
| 分子式 | C9H9NO4 |
| CAS号 | 199854-00-7 |
| 稳定性 | ≥ 2 years |
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