L-DOPA
货号：
13248-5g 基本售价：
196.0 元 规格：
5 g
产品信息
概述| 货号 | 13248-5g |
| 描述 | Dopamine is a neurotransmitter involved in synaptic plasticity, cognition, and the regulation of locomotor control. It is produced endogenously in the substantia nigra and ventral tegmental area but when administered exogenously cannot cross the blood brain barrier. L-DOPA is a metabolic precursor of dopamine that is capable of crossing the blood brain barrier. It is produced from L-tyrosine by trysosine hydroxylase and metabolized by catechol-O-methyl transferase (COMT). In the brain L-DOPA is converted to dopamine. It is conventionally used to increase dopamine concentrations in the brain as a treatment for Parkinson’s disease and stroke recovery.1 However L-DOPA has a short half-life and is known to elevate homocysteine concentrations in plasma, which can be neurotoxic and induce oxidative damage.2 |
| 别名 | 3,4-Dihydroxyphenylalanine;Levodopa;Pardopa;Syndopa; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Berends, H.I.,Nijlant, J.M.M.,Movig, K.L.L., et al. The clinical use of drugs influencing neurotransmitters in the brain to promote motor recovery after stroke; a Cochrane systematic review. European Journal of Physical and Rehabilitation Medicine 45(4), 621-630 (2009).
2.Müller, T. Possible treatment concepts for the levodopa-related hyperhomocysteinemia. Cardiovascular Psychiatry and Neurology 2009, (2009).
|
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | 22 |
| 纯度 | ≥95% |
| 计算分子量 | 197.2 |
| 分子式 | C9H11NO4 |
| CAS号 | 59-92-7 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
