2-cyano-Pyrimidine
货号:
10007121-1g 基本售价:
196.0 元 规格:
1 g
产品信息
概述货号 | 10007121-1g |
描述 | Cathepsin K is a lysosomal cysteine protease found in osteoclasts whose elevated activity has been linked to the formation of osteoporosis and arthritis.1 2-cyano-Pyrimidine is a cathepsin K inhibitor whose basic structure and derivatives are being studied for the treatment of osteoporosis. 2-cyano-Pyrimidine has an IC50 value of 170 nM for inhibition of cathepsin K.2 |
性能供应商 | Cayman |
应用文献 |
1.Altmann, E.,Aichholz, R.,Betschart, C., et al. 2-cyano-pyrimidines: A new chemotype for inhibitors of the cysteine protease cathepsin K. Journal of Medicinal Chemistry 50(4), 591-594 (2007). 2.Carroll, J.,Smith, N., and Babson, A.L. A colorimetric serum glucose determination using hexokinase and glucose-6-phosphate dehydrogenase. Biochemical Medicine 4, 171-180 (1970).
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运输条件 | Wet ice in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | >98% |
计算分子量 | 124.1 |
分子式 | C5H3N3 |
CAS号 | 14080-23-0 |
稳定性 | ≥ 2 years |
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