Mn(III)TMPyP
货号:
75852-10mg 基本售价:
182.0 元 规格:
10 mg
产品信息
概述货号 | 75852-10mg |
描述 | Mn(III)TMPyP is a manganese-porphyrin which acts as a superoxide dismutase (SOD) mimetic and peroxynitrite decomposition catalyst.1 SOD mimetics described to date are unstable and are capable of catalyzing undesired side-reactions in addition to the dismutation of the superoxide radical (O2-). Mn(III)TMPyP is an SOD mimetic with increased stability to pH and hydrogen peroxide. The rate constant for superoxide dismutation and peroxynitrite decomposition are 3.9 x 107 M−1s−1 and ~2 x 106 M−1s−1, respectively.1,2 Mn(III)TMPyP protected and enhanced the growth of SOD null E. coli with a doubling time of 60 minutes (as compared to 240 minutes of the control) at 25 µM.2 |
性能供应商 | Cayman |
应用文献 |
1.Hunt, J.,Lee, J., and Groves, J.T. Amphiphilic peroxynitrite decomposition catalysts in liposomal assemblies. Chemistry & Biology 4, 845-858 (1997). 2.Faulkner, K.M.,Liochev, S.I., and Fridovich, I. Stable Mn(III) porphyrins mimic superoxide dismutase in vitro and substitute for it in vivo. The Journal of Biological Chemisty 269, 23471-23476 (1994).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥95% |
计算分子量 | 909 |
分子式 | C44H36MnN8 ?5Cl |
稳定性 | ≥ 1 year |
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