LY83583
货号：
70230-1mg 基本售价：
182.0 元 规格：
1 mg
产品信息
概述| 货号 | 70230-1mg |
| 描述 | LY83583 is an inhibitor of soluble guanylate cyclase and of cGMP production. It inhibits soluble guanylate cyclase in human platelets with an IC50 value of 2 µM.1 LY83583 also inhibits leukotriene synthesis in guinea pig lung and rat peritoneal cells with an IC50 value of 1.8 µM and is a noncompetitive inhibitor of glutathione reductase in bovine intestinal mucosa with a Ki value of 3 µM.2,3 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Mülsch, A.,Lückhoff, A.,Pohl, U., et al. LY 83583 (6-anilino-5,8-quinolinedione) blocks nitrovasodilator-induced cyclic GMP increases and inhibition of platelet activation. Naunyn-Schmiedebergs Archives of Pharmacology 340, 119-125 (1989).
2.Fleisch, J.H.,Haisch, K.D.,Spaethe, S.M., et al. Pharmacologic analysis of two novel inhibitors of leukotriene (slow reacting substance) release. Journal of Pharmacology and Experimental Therapeutics 229, 681-689 (1984).
3.Lüönd, R.M.,McKie, J.H., and Douglas, K.T. A direct link between LY83583, a selective repressor of cyclic GMP formation, and glutathione metabolism. Biochemical Pharmacology 45, 2547-2549 (1993).
|
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥99% |
| 计算分子量 | 250.3 |
| 分子式 | C15H10N2O2 |
| CAS号 | 91300-60-6 |
| 稳定性 | ≥ 1 year |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
