BW 723C86
货号：
70090-1mg 基本售价：
182.0 元 规格：
1 mg
产品信息
概述| 货号 | 70090-1mg |
| 描述 | The transduction of neurobehavioral effects by serotonin (5-hydroxy tryptamine; 5-HT) is mediated via at least 6 major 5-HT receptor subtypes. Non-selective 5-HT receptor agonists, such as mCPP, induce many behavioral responses in rats, including increased anxiety, hypophagia, and hypoactivity. BW 723C86 is in fact anxiolytic, and its only other prominent behavioral effect is hyperphagia.1 This effect is likely due to the 10-fold selectivity of BW 723C86 for the HT2B receptor.2 Direct infusion of 1-3 µg of BW 723C86 into the cerebral ventricles of rats evokes maximal behavioral responses; the response was attenuated at both higher and lower doses.2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Kennett, G.A.,Bright, F.,Trail, B., et al. Effects of the 5-HT2B receptor agonist, BW 723C86, on three rat models of anxiety. British Journal of Pharmacology 117, 1443-1448 (1996).
2.Kennett, G.A.,Ainsworth, K.,Trail, B., et al. BW 723C86, a 5-HT2B receptor agonist, causes hyperphagia and reduced grooming in rats. Neuropharmacology 36, 233-239 (1997).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 322.9 |
| 分子式 | C16H18N2OS • HCl |
| CAS号 | 160521-72-2 |
| 稳定性 | ≥ 2 years |
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