17-Octadecynoic Acid
货号：
90270-1mg 基本售价：
154.0 元 规格：
1 mg
产品信息
概述| 货号 | 90270-1mg |
| 描述 | 17-Octadecynoic Acid (17-ODYA) is a fatty acid analog with an ω-terminal acetylene. It is a suicide inhibitor of leukotriene B4 20-hydroxylase and renal CYP450 ω-hydroxylase.1,2 At a concentration of 10 µM, 17-ODYA completely inhibits the bradykinin-dependent transport of sodium chloride in rat TALH cells.2 |
| 别名 | Alk-16;17-ODYA; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Shak, S.,Reich, N.O.,Goldstein, I.M., et al. Leukotriene B4 ω-hydroxylase in human polymorphonuclear leukocytes. Suicidal inactivation by acetylenic fatty acids. The Journal of Biological Chemisty 260, 13023-13028 (1985).
2.Grider, J.S.,Falcone, J.C.,Kilpatrick, E.L., et al. P450 arachidonate metabolites mediate bradykinin-dependent inhibition of NaCl transport in the rat thick ascending limb. Canadian Journal of Physiology and Pharmacology 75, 91-96 (1997).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 280.5 |
| 分子式 | C18H32O2 |
| CAS号 | 34450-18-5 |
| 稳定性 | ≥ 1 year |
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