| 货号 | 10724-1mg |
| 描述 | Ceramides are generated from sphingomyelin through activation of sphingomyelinases or through the de novo synthesis pathway. Certain forms of ceramide have been shown to mediate cellular responses such as apoptosis, growth arrest, and differentiation in certain cell types.1,2 C-20 Ceramide is a natural 20:0 ceramide that is abundant in the brain. It is synthesized de novo by ceramide synthases 1 and 2.3,4 |
| 别名 | C20 Ceramide (d18:1/20:0);N-arachidoyl-D-erythro-sphingosine; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Ogretmen, B.,Pettus, B.J.,Rossi, M.J., et al. Biochemical mechanisms of the generation of endogenous long chain ceramide in response to exogenous short chain ceramide in the A547 human lung adenocarcinoma cell line. The Journal of Biological Chemisty 277(15), 12960-12969 (2002). 2.Pandey, S.,Murphy, R.F. and Agrawal, D.K. Recent advances in the immunobiology of ceramide. Exp.Mol.Pathol. 82(3), 298-309 (2007). 3.Cowart, L.A. Sphingolipids: Players in the pathology of metabolic disease. Trends in Endocrinology and Metabolism 20(1), 34-42 (2008). 4.Pewzner-Jung, Y.,Ben-Dor, S. and Futerman, A.H. When do lasses (longevity assurance genes) become CerS (ceramide synthases)? The Journal of Biological Chemisty 281(35), 25001-25005 (2006). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 594 |
| 分子式 | C38H75NO3 |
| CAS号 | 1988419 |
| 稳定性 | ≥ 2 years |
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