F16
货号：
10022-1mg 基本售价：
126.0 元 规格：
1 mg
产品信息
概述| 货号 | 10022-1mg |
| 描述 | F16 is a small, cationic, lipophilic molecule which binds preferentially to mitochondrial membranes and disrupts their function.1 F16 was discovered in high throughput screens for tumor inhibitors, where it was found to induce apoptosis in HER-1/EGFR-expressing breast carcinoma cell lines. In addition to being a potential antitumor agent, F16 is an easily visualized fluorescent molecule which can also be used to visualize mitochondria under confocal microscopy. The mechanism of apoptosis induction by F16 is believed to be through disruption of the mitochondrial transmembrane potential.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Fantin, V.R.,Berardi, M.J.,Scorrano, L., et al. A novel mitochondriotoxic small molecule that selectively inhibits tumor cell growth. Cancer Cell 2, 29-42 (2002).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 362.2 |
| 分子式 | C16H15N2 • I |
| CAS号 | 36098-33-6 |
| 稳定性 | ≥ 2 years |
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