| 货号 | 70430-25g |
| 描述 | Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Guaiacol is readily oxidized by the heme iron of peroxidases including the peroxidase of cyclooxygenase (COX) enzymes. It therefore serve as a reducing co-substrate for COX reactions.1 The color yield per peroxide at 470 nm is 6,650 (M peroxide reduced)-1 cm-1.2,3,4 Two moles of guaiacol are oxidized for each mole of hydroperoxide reduced by the peroxidase. The resulting guaiacol chromophore can be used for the colorimetric determination of hydroperoxidase activity. |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Markey, C.M.,Alward, A.,Weller, P.E., et al. Quantitative studies of hydroperoxide reduction by prostaglandin H synthase. Reducing substrate specificity and the relationship of peroxidase to cyclooxygenase activities. The Journal of Biological Chemisty 262, 6266-6279 (1987). 2.Doerge, D.R.,Divi, R.L., and Churchwell, M.I. Identification of the colored guaiacol oxidation product produced by peroxidases. Analytical Biochemistry 250, 10-17 (1997). 3.Kulmacz, R.J., and Lands, W.E.M. Quantitative similarities in the several actions of cyanide on prostaglandin H synthase. Prostaglandins 29, 175-190 (1985). 4.Marquez, L.A., and Dunford, H.B. Mechanism of the oxidation of 3,5,3,5-tetramethylbenzidine by myeloperxidase determined by transient-and steady-state kinetics. Biochemistry 36, 9349-9355 (1997). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | 22 |
| 纯度 | ≥98% |
| 计算分子量 | 124.1 |
| 分子式 | C7H8O2 |
| CAS号 | 90-05-1 |
| 稳定性 | ≥ 1 year |
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