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货号： bs-1583R 基本售价： 780.0 元 规格： 50ul
- 规格：50ul
- 价格：780.00元
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-1583R
- 英文名称
- SFTPD
- 中文名称
- 肺表面活性蛋白D抗体
- 别 名
- SFTPD surfactant protein D; pulmonary surfactant-associated glycoprotein D; COLEC 7; COLEC7; Collectin7; PSP D; PSPD; Pulmonary surfactant apoprotein; Pulmonary surfactant associated protein D; SFTP 4; SFTP4; SFTPD; SP D; Surfactant associated protein pulmonary 4; Surfactant pulmonary associated protein D; SFTPD_HUMAN; Pulmonary surfactant-associated protein D; PSP-D; SP-D; Collectin-7; Lung surfactant protein D.
- Specific References (2) | bs-1583R has been referenced in 2 publications.[IF=2.94] Sung, Hsin-Ching, et al. "The protective effect of eupafolin against TNF-α-induced lung inflammation via the reduction of intercellular cell adhesion molecule-1expression." Journal of Ethnopharmacology (2015). IHC-P ; Mouse.PubMed:25975517[IF=4.92] Ferretti, Andrew, et al. "Autoantibody-Mediated Pulmonary Alveolar Proteinosis in Rasgrp1-Deficient Mice." The Journal of Immunology (2016): 1502248. IHC-P ; Mouse.PubMed:27279372
- 规格价格
- 50ul/780元购买 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 50ul 100ul 200ul
- 研究领域
- 肿瘤 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 41kDa
- 细胞定位
- 分泌型蛋白
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SP-D:301-375/375
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
Surfactant protein D contributes to the lungs defense against inhaled microorganisms. Its a calcium ion dependent carbohydrate binding protein and is structurally similar to other C type mammalian lectins, such as conglutinin and SPA. It has a molecular size of approximately 37-43kDa in its reduced state, 620kDa in non dissociating conditions. Surfactant protein D enhances the production of oxygen radicals by rat alveolar macrophages and regulates some actions of SPA, which is the most abundant surfactant protein. Surfactant protein D is synthesized and secreted by alveolar epithelial type II cells.
Function:
Contributes to the lungs defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
Subunit:
Oligomeric complex of 4 set of homotrimers.
Subcellular Location:
Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film.
Post-translational modifications:
The N-terminus is blocked.
Hydroxylation on proline residues within the sequence motif, GXPG, is most likely to be 4-hydroxy as this fits the requirement for 4-hydroxylation in vertebrates.
Similarity:
Belongs to the SFTPD family.
Contains 1 C-type lectin domain.
Contains 1 collagen-like domain.
SWISS:
P35247
Gene ID:
6441
Database links:Entrez Gene: 6441 Human
Entrez Gene: 20390 Mouse
Entrez Gene: 25350 Rat
Omim: 178635 Human
SwissProt: P35247 Human
SwissProt: P50404 Mouse
SwissProt: P35248 Rat
Unigene: 253495 Human
Unigene: 1321 Mouse
Unigene: 11348 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
- 产品图片
Formalin-fixed and paraffin embedded mouse lung tissue labeled Anti-SP-D Polyclonal Antibody, Unconjugated (bs-1583R) at 1:2000, followed by conjugation to the secondary antibody and DAB staining