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Anti-Histone H3.1

货号: bs-17422R 基本售价: 1380.0 元 规格: 100ul

规格:100ul
价格:1380.00元
规格:200ul
价格:2200.00元

产品信息

产品编号
bs-17422R
英文名称
Histone H3.1
中文名称
组蛋白H3.1抗体
别    名
H3 histone family, member A; H3 histone family, member B; H3 histone family, member C; H3 histone family, member D; H3 histone family, member E; H3 histone family, member F; H3 histone family, member G; H3 histone family, member H; H3 histone family, member I; H3 histone family, member J; H3 histone family, member K; H3 histone family, member L; H3.1; H3.f; H3/A; H3/c; H3/d; H3/f; H3/h; H3/i; H3/j; H3/k; H3/l; H31_HUMAN; H3F1K; H3FA; H3FB; H3FC; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; HIST1 cluster H3A; HIST1 cluster H3B; HIST1 cluster H3C; HIST1 cluster H3D; HIST1 cluster H3E; HIST1 cluster H3F; HIST1 cluster H3G; HIST1 cluster H3I; HIST1 cluster H3J; HIST1H3A; HIST1H3B; HIST1H3C; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J; histone 1, H3a; histone 1, H3b; Histone 1, H3c; Histone 1, H3e; histone 1, H3f; histone 1, H3g; histone 1, H3h; histone 1, H3i; histone 1, H3j; histone cluster 1, H3a; histone cluster 1, H3b; Histone cluster 1, H3c; Histone cluster 1, H3e; histone cluster 1, H3g; histone cluster 1, H3h; histone cluster 1, H3i; histone cluster 1, H3j; Histone gene cluster 1 H3A; Histone gene cluster 1 H3B; Histone gene cluster 1 H3E; Histone gene cluster 1 H3F; Histone gene cluster 1 H3G; Histone gene cluster 1, H3; Histone gene cluster 1, H3C; Histone gene cluster 1, H3D; Histone gene cluster 1, H3I; Histone gene cluster 1, H3IH; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l  
规格价格
100ul/1380元购买    200ul/2200元购买    大包装/询价
说 明 书
100ul  200ul
研究领域
细胞生物  表观遗传学  
抗体来源
Rabbit
克隆类型
Polyclonal
交叉反应
Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Chimpanzee, 
产品应用
WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量
15kDa
细胞定位
细胞核 
性    状
Lyophilized or Liquid
浓    度
1mg/ml
免 疫 原
KLH conjugated synthetic peptide derived from human Histone H3.1:71-136/136 
亚    型
IgG
纯化方法
affinity purified by Protein A
储 存 液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed
PubMed
产品介绍
background:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Jul 2008]

Function:
Histone H3.1 is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodelling. The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3 H4 heterotetramer and two H2A H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

Subcellular Location:
Nuclear

Similarity:
Belongs to the histone H3 family.

SWISS:
P68431

Gene ID:
8350

Database links:

Entrez Gene: 8350Human

Entrez Gene: 8351Human

Entrez Gene: 8352Human

Entrez Gene: 8353Human

Entrez Gene: 8354Human

Entrez Gene: 8355Human

Entrez Gene: 8356Human

Entrez Gene: 8357Human

Entrez Gene: 8358Human

Entrez Gene: 8968Human

Entrez Gene: 319148Mouse

Entrez Gene: 319151Mouse

Entrez Gene: 319152Mouse

Entrez Gene: 319153Mouse

Entrez Gene: 360198Mouse

Entrez Gene: 97908Mouse

Omim: 602810Human

Omim: 602811Human

Omim: 602812Human

Omim: 602813Human

Omim: 602814Human

Omim: 602815Human

Omim: 602816Human

Omim: 602817Human

Omim: 602818Human

Omim: 602819Human

SwissProt: P68431Human

SwissProt: P68433Mouse

Unigene: 132854Human

Unigene: 247813Human

Unigene: 247814Human

Unigene: 248176Human

Unigene: 443021Human

Unigene: 484990Human

Unigene: 532144Human

Unigene: 533292Human

Unigene: 546315Human

Unigene: 586261Human

Unigene: 591778Human

Unigene: 626666Human

Unigene: 221301Mouse

Unigene: 261657Mouse

Unigene: 377874Mouse

Unigene: 390558Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品图片
Sample:A549 Cell (Human) Lysate at 40 ug
Primary: Anti-Histone H3.1(bs-17422R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 15kD
Observed band size: 15kD
Sample:TT Cell (Human) Lysate at 40 ug
Primary: Anti-Histone H3.1(bs-17422R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 15kD
Observed band size: 15kD
Sample:Stomach (Mouse) Lysate at 40 ug
Primary: Anti-Histone H3.1(bs-17422R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 15kD
Observed band size: 15kD
Sample:U251 Cell (Human) Lysate at 40 ug
Primary: Anti-Histone H3.1(bs-17422R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 15kD
Observed band size: 15kD
Sample:A431 Cell(Human)Lysate at 40 ug
Primary: Anti-Histone H3.1(bs-17422R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 15kD
Observed band size: 15kD