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货号： bs-4243R-Bio 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-4243R-Bio
- 英文名称
- Anti-ITPR2/Biotin
- 中文名称
- 生物素标记的5-三磷酸肌醇受体2抗体
- 别 名
- 4; 5-trisphosphate receptor; Inositol 1 4 5 trisphosphate receptor type 2; Inositol 1,4,5-trisphosphate receptor type 2; Inositol 145 trisphosphate receptor type 2; InsP3 R2; InsP3R2; IP3 R2; IP3 receptor isoform 2; IP3R 2; IP3R2; ITPR 2; Itpr2; ITPR2_HUMAN; Type 2 inositol 1 4 5 trisphosphate receptor; Type 2 inositol 1; Type 2 inositol 145 trisphosphate receptor; Type 2 InsP3 receptor.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 免疫学 信号转导 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow,
- 产品应用
- ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 308kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ITPR2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
Function:
Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA (By similarity).
Subunit:
Homotetramer. Interacts with CABP1.
Subcellular Location:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue Specificity:
Isoform Short is found in skeletal muscle and heart.
Post-translational modifications:
Phosphorylation by cAMP-dependent PKA on Ser-937 increases calcium release.
Similarity:
Belongs to the InsP3 receptor family.
Contains 5 MIR domains.
Database links:Entrez Gene: 281878 Cow
Entrez Gene: 3709 Human
Entrez Gene: 16439 Mouse
Entrez Gene: 81678 Rat
Omim: 600144 Human
SwissProt: Q8WN96 Cow
SwissProt: Q14571 Human
SwissProt: Q9Z329 Mouse
SwissProt: P29995 Rat
Unigene: 512235 Human
Unigene: 393003 Mouse
Unigene: 7800 Mouse
Unigene: 89152 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.