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货号： bs-5706R-Bio 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-5706R-Bio
- 英文名称
- Anti-RASSF4/Biotin
- 中文名称
- 生物素标记的Ras相关区域家族蛋白4抗体
- 别 名
- AD037; Ras association (RalGDS/AF 6) domain family 4; Ras association domain family 4; Ras association (RalGDS/AF 6) domain family member 4; Ras association domain containing protein 4; RASSF 4; Tumor suppressor RASSF4; RASF4_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 信号转导 细胞周期蛋白 G蛋白偶联受体
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,
- 产品应用
- WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 37kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human RASSF4
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The function of RASSF4 has not yet been determined but it may involve a role in tumor suppression. RASSF4 may act as a KRAS effector protein and may promote apoptosis and cell cycle arrest. Alternative splicing of this gene results in several transcript variants; however, most of the variants have not been fully described.
Function:
Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest.
Subunit:
Interacts directly with activated KRAS in a GTP-dependent manner.
Tissue Specificity:
Widely expressed. Frequently down-regulated in tumor cell lines.
Similarity:
Contains 1 Ras-associating domain.
Contains 1 SARAH domain.
Database links:Entrez Gene: 83937 Human
Entrez Gene: 213391 Mouse
Entrez Gene: 362423 Rat
Omim: 610559 Human
SwissProt: Q9H2L5 Human
SwissProt: Q8CB96 Mouse
SwissProt: Q566C5 Rat
Unigene: 522895 Human
Unigene: 257931 Mouse
Unigene: 195253 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.