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货号： bs-5722R-Bio 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-5722R-Bio
- 英文名称
- Anti-RASL10A/Biotin
- 中文名称
- 生物素标记的Ras样蛋白家族10A抗体
- 别 名
- Ras like protein family member 10A; Ras like protein RRP22; RAS like, family 10, member A; RAS related on chromosome 22; Ras related protein on chromosome 22; Ras related protein on chromosome 22 homolog; RASL10A protein; Rasl10a RAS like, family 10, member A; RP23 64E17.6 antibody RRP22; RSLAA_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 23kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human RASL10A
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Ras proteins are members of a superfamily of related small GTPases. RRP22 can be posttranslationally modified by farnesyl. RRP22 inhibits cell growth and promotes caspase-independent cell death. The specific function of RASL10A is not yet known.
Function:
Potent inhibitor of cellular proliferation.
Subunit:
Interacts with UBF/UBTF.
Subcellular Location:
Cell membrane, Cytoplasmic side. Nucleus, nucleolus. Note=May cycle in and out of the nucleolus in a GTP-dependent manner.
Tissue Specificity:
Expression appears to be strictly limited to the central nervous system.
Post-translational modifications:
Isoprenylation is essential for nucleolar localization, and the proliferation-inhibiting activity of RASL10A.
Similarity:
Belongs to the small GTPase superfamily. Ras family.
Database links:Entrez Gene: 10633 Human
Entrez Gene: 75668 Mouse
Entrez Gene: 364190 Rat
Omim: 602220 Human
SwissProt: Q92737 Human
SwissProt: Q8K5A4 Mouse
Unigene: 73088 Human
Unigene: 374836 Mouse
Unigene: 50230 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.