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货号： bs-5995R-Bio 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-5995R-Bio
- 英文名称
- Anti-CAMTA1/Biotin
- 中文名称
- 生物素标记的钙调蛋白结合转录激活因子1抗体
- 别 名
- Calmodulin-binding transcription activator 1; Calmodulin binding transcription activator 1; CMTA1; KIAA0833; CMTA1_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 染色质和核信号
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 183kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CAMTA1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
CAMTA1 is a transcription activator which is a putatuove tumor suppressor. It is thought to interact with calmodulin. Defects in CAMTA1 are detected in patients with oligodendroglioma and astrocytoma.
Function:
Transcriptional activator. May act as a tumor suppressor.
Subunit:
May interact with calmodulin (Potential).
Subcellular Location:
Nucleus (Probable). Cytoplasm.
Tissue Specificity:
Normally expressed in non-neoplastic adult central nervous system tissues: detected in whole brain, cerebellum, brain cortex, occipital lobe, frontal lobe, temporal lobe, putamen. Expression levels are low in oligodendroglial tumors, and are reduced by half in oligodendroglioma and astrocytoma cases with 1p loss of heterozygosity. Detected in neuroblastic-type cultured neuroblastoma cells. Expressed in heart and kidney.
Similarity:
Belongs to the CAMTA family.
Contains 3 ANK repeats.
Contains 1 CG-1 DNA-binding domain.
Contains 1 IPT/TIG domain.
Contains 3 IQ domains.
Database links:Entrez Gene: 23261 Human
Entrez Gene: 100072 Mouse
Omim: 611501 Human
SwissProt: Q9Y6Y1 Human
SwissProt: A2A898 Mouse
Unigene: 397705 Human
Unigene: 671020 Human
Unigene: 318846 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.