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货号： bs-6216R-Bio 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-6216R-Bio
- 英文名称
- Anti-ROR beta/Biotin
- 中文名称
- 生物素标记的维甲酸相关孤儿受体β抗体
- 别 名
- bA133M9.1; NR1F2; Nuclear receptor ROR-beta; Nuclear receptor RZR beta; Nuclear receptor RZR-beta; Nuclear receptor subfamily 1 group F member 2; OTTHUMP00000021486; RAR related orphan receptor B; RAR related orphan receptor beta; Retinoic acid binding receptor beta; Retinoid-related orphan receptor-beta; ROR BETA; Rorb; RORB_HUMAN; RZR BETA; RZRB.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 染色质和核信号 神经生物学 信号转导 细胞周期蛋白 细胞分化 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse, Sheep,
- 产品应用
- WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 53kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human RORB
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
ROR beta is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation.
Function:
Orphan nuclear receptor required for normal postnatal development of rod and cone photoreceptor cells. Regulates transcription of OPN1SW in cone photoreceptor cells by binding the sequence 5-AGGTCA-3 in the OPN1SW promoter (By similarity).
Subcellular Location:
Nucleus (Probable).
Similarity:
Belongs to the nuclear hormone receptor family. NR1 subfamily.
Contains 1 nuclear receptor DNA-binding domain.
Database links:Entrez Gene: 6096 Human
Entrez Gene: 225998 Mouse
Entrez Gene: 309288 Rat
Omim: 601972 Human
SwissProt: Q92753 Human
SwissProt: Q8R1B8 Mouse
SwissProt: P45446 Rat
Unigene: 494178 Human
Unigene: 234641 Mouse
Unigene: 210157 Rat
Unigene: 231652 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.