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货号： bs-6730R-Bio 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-6730R-Bio
- 英文名称
- Anti-Upstream Binding Protein 1/Biotin
- 中文名称
- 生物素标记的上游结合蛋白1抗体
- 别 名
- LBP 1a; Cp2b; DKFZp686L1745; LBP 1a; LBP 1B; LBP1; LBP1A; LBP1B; NF2d9; Upstream binding protein 1; Transcription factor LBP-1; UBIP1_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 信号转导 转录调节因子 结合蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,
- 产品应用
- WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 60kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Upstream Binding Protein 1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.
Function:
UBP1 is an important SF1 independent transcriptional activator stimulating P450scc expression in human placental JEG 3 cells.
Subunit:
Interacts with TFCP2. Interacts with PIAS1, and is probably part of a complex containing TFCP2, UBP1 and PIAS1.
Subcellular Location:
Nucleus.
Tissue Specificity:
Expressed in adrenal tissue, JEG-3, NCI-H295A, HepG2 and HeLa cell lines.
Similarity:
Belongs to the grh/CP2 family. CP2 subfamily.
Database links:Entrez Gene: 7342 Human
Entrez Gene: 22221 Mouse
Entrez Gene: 301038 Rat
Omim: 609784 Human
SwissProt: Q86Y57 Human
SwissProt: Q9NZI7 Human
SwissProt: Q60786 Mouse
SwissProt: Q811S7 Mouse
SwissProt: Q8BH21 Mouse
Unigene: 118041 Human
Unigene: 729120 Human
Unigene: 28052 Mouse
Unigene: 386808 Mouse
Unigene: 15705 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.